Development of new inhibitors for the type II transmembrane serine protease matriptase

Development of new inhibitors for the type II transmembrane serine protease matriptase

Several new inhibitors were prepared and tested as potential matriptase inhibitors. The most potent compounds were found among the tertiary amides of arylsulfonylated-3-amidinophenylalanines. The incorporation of suitable bis-substituted biphenylsulfonyl groups in combination with appropriate C-term...

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Autore principale: Hammami Maya
Altri autori: Steinmetzer, Torsten (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2012
Soggetti:
Matriptase
H9N2 influenza virus
Cancer, Influenza
Inhibitors
Naturwissenschaften
Serinprotease
Cancer
Natural sciences & mathematics
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