Development of new inhibitors for the type II transmembrane serine protease matriptase

Several new inhibitors were prepared and tested as potential matriptase inhibitors. The most potent compounds were found among the tertiary amides of arylsulfonylated-3-amidinophenylalanines. The incorporation of suitable bis-substituted biphenylsulfonyl groups in combination with appropriate C-term...

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Autor principal: Hammami Maya
Otros Autores: Steinmetzer, Torsten (Prof. Dr.) (Orientador)
Formato: Dissertation
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2012
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Acceso en línea:Texto Completo PDF
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