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Elucidation of mechanism of disease resistance and persistence in chronic myeloid leukemia.
Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell caused by the BCR-ABL receptor tyrosine kinase. Imatinib mesylate (IM) is an inhibitor of BCR-ABL and has been approved for the treatment of CML. IM is well tolerated and highly efficacious as it induces stable long-t...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2011
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| 在线阅读: | PDF-Volltext |
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