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Elucidation of mechanism of disease resistance and persistence in chronic myeloid leukemia.
Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell caused by the BCR-ABL receptor tyrosine kinase. Imatinib mesylate (IM) is an inhibitor of BCR-ABL and has been approved for the treatment of CML. IM is well tolerated and highly efficacious as it induces stable long-t...
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| Formato: | Dissertation |
| Lenguaje: | inglés |
| Publicado: |
Philipps-Universität Marburg
2011
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| Materias: | |
| Acceso en línea: | Texto Completo PDF |
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