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Elucidation of mechanism of disease resistance and persistence in chronic myeloid leukemia.
Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell caused by the BCR-ABL receptor tyrosine kinase. Imatinib mesylate (IM) is an inhibitor of BCR-ABL and has been approved for the treatment of CML. IM is well tolerated and highly efficacious as it induces stable long-t...
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| Format: | Doctoral Thesis |
| Language: | English |
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Philipps-Universität Marburg
2011
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| Online Access: | PDF Full Text |
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