The role of 12/15-lipoxygenases in ROS-mediated neuronal cell death

The role of 12/15-lipoxygenases in ROS-mediated neuronal cell death

Oxidative stress has been established as a key trigger of neuronal dysfunction and death in age-related neurodegenerative diseases and in delayed neuronal death after acute brain injury by ischemic stroke or brain trauma. Despite increasing knowledge on the toxicity of reactive oxygen species (ROS)...

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Autore principale: Tobaben, Svenja
Altri autori: Culmsee, Carsten (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2011
Soggetti:
Mitochondrium
Bid
Lipoxygenases
Nervenzelle
Oxidative stress
Bcl-2-Proteinfamilie
Apoptosis
Medizin
Arachidons�ure
Mitochondria
Oxidativer Stress
Lipoxygenasen
Medical sciences Medicine
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