The Neuropeptide PACAP Mediates Stimulus-Transcription Coupling in Hypothalamic-Pituitary-Adrenocortical Axis and Sympathetic Nervous System - Implications for Acute and Chronic Stress Responses

The Neuropeptide PACAP Mediates Stimulus-Transcription Coupling in Hypothalamic-Pituitary-Adrenocortical Axis and Sympathetic Nervous System - Implications for Acute and Chronic Stress Responses

Stress is a vital response of all organisms to the demands of life. By adjusting to stimuli from the outside world, and stimuli arising from its internal organs, the body is continually at work to ensure its proper function under a widely variable range of conditions. Thus, acute and adequate respon...

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Bibliographic Details
Main Author: Stroth, Nikolas
Contributors: Weihe, Eberhard (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2011
Subjects:
Neuroendokrines System
Transkriptionsfaktor
Sympathetic Nervous System
PACAP
Neuropeptide
Corticoliberin
Naturwissenschaften
Stress
Stressreaktion
Sympathikus
HPA axis
Natural sciences & mathematics
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1. Pituitary adenylate cyclase-activating polypeptide mediates differential signaling through PAC1 receptor splice variants and activates non-canonical cAMP dependent gene induction in the nervous system - Implications for homeostatic stress-responding

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