Synthese nicht-peptidischer Plasmepsin II- und IV-Inhibitoren

Basierend auf dem Grundgerüst eines 2,3,4,7-Tetrahydro-1H-azepins ist die Optimierung zu nanomolaren Plasmepsin II-Inhibitoren zur Adressierung der katalytischen Diade in Aspartyl-Proteasen gelungen. Ausgehend von (rac)-3,5-Bis-hydroxymethyl-2,3,4,7-tetrahydro-1H-azepin, welches mit seinem vermutlic...

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Bibliographic Details
Main Author: Brass, Nan-Si
Format: Doctoral Thesis
Language:German
Published: Philipps-Universität Marburg 2010
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Call Number: urn:nbn:de:hebis:04-z2010-01263
Publication Date: 2010-04-27
Downloads: 25 (2022), 70 (2021), 89 (2020), 64 (2019), 39 (2018)
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2010/0126
https://doi.org/10.17192/z2010.0126