The Role of the Mitotic Spindle Checkpoint in Chemotherapy-Induced Apoptosis

The Role of the Mitotic Spindle Checkpoint in Chemotherapy-Induced Apoptosis

The mitotic spindle assembly checkpoint (SCP) is a signal transduction pathway that ensures proper chromosome segregation during mitosis by inhibiting the onset of anaphase until all chromosomes are properly aligned. It requires a group of highly conserved proteins including Mad1, Mad2, Bub1, BubR1,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Vogel, Celia
Awduron Eraill: Bastians, Holger (Dr.) (Cynghorydd traethodau ymchwil)
Fformat: Dissertation
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2008
Pynciau:
Mitotic spindle checkpoint
Chemotherapie
Cell cycle
Mitotic catastrophe
Mitotischer Spindelcheckpoint
Apoptose
Apoptosis
Zellzyklus
Mitotische Katastrophe
Medizin
Chemotherapy
Medical sciences Medicine
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