The Role of the Mitotic Spindle Checkpoint in Chemotherapy-Induced Apoptosis

The Role of the Mitotic Spindle Checkpoint in Chemotherapy-Induced Apoptosis

The mitotic spindle assembly checkpoint (SCP) is a signal transduction pathway that ensures proper chromosome segregation during mitosis by inhibiting the onset of anaphase until all chromosomes are properly aligned. It requires a group of highly conserved proteins including Mad1, Mad2, Bub1, BubR1,...

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Bibliografiske detaljer
Hovedforfatter: Vogel, Celia
Andre forfattere: Bastians, Holger (Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2008
Fag:
Mitotic spindle checkpoint
Chemotherapie
Cell cycle
Mitotic catastrophe
Mitotischer Spindelcheckpoint
Apoptose
Apoptosis
Zellzyklus
Mitotische Katastrophe
Medizin
Chemotherapy
Medical sciences Medicine
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Klassifikationsnummer: urn:nbn:de:hebis:04-z2009-01035
Publikationsdatum: 2009-03-26
Datum der Annahme: 2008-08-05
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2009/0103
https://doi.org/10.17192/z2009.0103

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