Non-Viral Gene Delivery Systems: Studies on HER2-Targeted PEG-PEI Copolymers and Modified Chitosans

Non-Viral Gene Delivery Systems: Studies on HER2-Targeted PEG-PEI Copolymers and Modified Chitosans

In this thesis new non-viral gene delivery systems were synthesized and characterized. In the first part different questions concerning in vitro and in vivo gene delivery using HER2-targeted Polyethylenglycol (PEG)-modified Polyethylenimine (PEI) polyplexes were addressed. The second part deals with...

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Bibliografiska uppgifter
Huvudupphovsman: Germershaus, Oliver
Övriga upphovsmän: Kissel, Thomas (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:engelska
Publicerad: Philipps-Universität Marburg 2008
Ämnen:
Gentransfer
Polyethylenimin
Modified Polymers
Gene therapy
Polyethylenimine
Biodistribution
Modifizierte Polymere
Naturwissenschaften
Tiermodell
Polyethyleniminderivate
Pharmakokinetik
Plasmid
Pharmacokinetics
Zellkultur
Natural sciences & mathematics
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