Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

Daffis, Stephane

Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

Yellow fever virus (YFV) is a mosquito-transmitted, enveloped, positive stranded RNA virus belonging to the genus flavivirus, which causes hemorrhagic fever in humans in Africa and South America. The YFV is responsible for 200 000 clinical infections per year including 40 000 deaths. Despite the pre...

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Bibliografiska uppgifter
Huvudupphovsman:	Daffis, Stephane
Övriga upphovsmän:	ter Meulen, Jan (Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp:	Dissertation
Språk:	engelska
Publicerad:	Philipps-Universität Marburg 2006
Ämnen:	Gelbfieber Flaviviren Yellow fever virus Antibody fragments Gelbfiebervirus Phagen-Display-Bibliothek Neutralizing epitopes Impfstoff Virologie Medizin Phage display Medical sciences Medicine
Länkar:	PDF-fulltext
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Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

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