Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

Yellow fever virus (YFV) is a mosquito-transmitted, enveloped, positive stranded RNA virus belonging to the genus flavivirus, which causes hemorrhagic fever in humans in Africa and South America. The YFV is responsible for 200 000 clinical infections per year including 40 000 deaths. Despite the pre...

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Главный автор: Daffis, Stephane
Другие авторы: ter Meulen, Jan (Dr.) (Научный руководитель)
Формат: Dissertation
Язык:английский
Опубликовано: Philipps-Universität Marburg 2006
Предметы:
Gelbfieber
Flaviviren
Yellow fever virus
Antibody fragments
Gelbfiebervirus
Phagen-Display-Bibliothek
Neutralizing epitopes
Impfstoff
Virologie
Medizin
Phage display
Medical sciences Medicine
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