Concepts to Interfere with Protein-Protein Complex Formations: Data Analysis, Structural Evidence and Strategies for Finding Small Molecule Modulators

Concepts to Interfere with Protein-Protein Complex Formations: Data Analysis, Structural Evidence and Strategies for Finding Small Molecule Modulators

(1) Analyzing protein-protein interactions at the atomic level is critical for our understanding of the principles governing the interactions involved in protein-protein recognition. For this purpose descriptors explaining the nature of different protein-protein complexes are desirable. In this work...

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Autore principale: Block, Peter
Altri autori: Klebe, Gerhard (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2005
Soggetti:
Medizin
Database
Virtual screening
Machine learning
Medical sciences Medicine
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Collocazione: urn:nbn:de:hebis:04-z2005-06865
Data di pubblicazione: 2005-12-13
Datum der Annahme: 2005-12-16
Downloads: 18 (2024), 46 (2023), 70 (2022), 78 (2021), 87 (2020), 144 (2019), 45 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL di accesso: https://archiv.ub.uni-marburg.de/diss/z2005/0686
https://doi.org/10.17192/z2005.0686

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