Chitosan copolymers for intranasal delivery of insulin: synthesis, characterization and biological properties

Recently, chitosan has been extensively investigated as a promising carrier in the field of drug delivery. To overcome its poor solubility at physiological pH and the cytotoxicity of trimethyl chitosan, PEGylated trimethyl chitosan copolymers were synthesized and characterized systemically for the f...

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主要作者: Mao, Shirui
其他作者: Kissel, Thomas (Prof.) (BetreuerIn (Doktorarbeit))
格式: Dissertation
語言:英语
出版: Philipps-Universität Marburg 2004
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