Mitogenic signaling by Gq/11-coupled receptors

By binding to their cognate GPCRs, many potent mitogens such as neuropeptides, angiotensin II or lysophosphatidic acid stimulate cell proliferation via engaging the ERK/MAPK cascade. As mentioned before, agonists stimulating Gq/11-coupled receptors activate PLCb isoforms thereby...

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Bibliographic Details
Main Author: Roelle, Susanne
Contributors: Carell, Thomas, Prof. Dr. (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2004
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