In-Hospital Mortality in Patients with and without Dementia across Age Groups, Clinical Departments, and Primary Admission Diagnoses
Background: Studies have reported higher in-hospital mortality rates in patients living with dementia (PlwD) with limited evidence across age groups, clinical departments, and admission diagnoses. The aim of this study was to compare the in-hospital mortality rate of PlwD with patients without de...
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| Autori principali: | , , |
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| Natura: | Articolo |
| Lingua: | inglese |
| Pubblicazione: |
Philipps-Universität Marburg
2024
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| Soggetti: | |
| Accesso online: | PDF Full Text |
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| Riassunto: | Background: Studies have reported higher in-hospital mortality rates in patients living with
dementia (PlwD) with limited evidence across age groups, clinical departments, and admission diagnoses.
The aim of this study was to compare the in-hospital mortality rate of PlwD with patients
without dementia across groups, clinical departments, and admission diagnoses. Methods: This casecontrol
study included patients aged ≥ 60 years hospitalized in 1 of 14 German hospitals between
January 2019 and July 2023. PlwD were matched to patients without dementia. The associations
between dementia and in-hospital mortality across groups were assessed using univariable logistic
regression analyses. Results: 15,956 patients with and 15,956 without dementia were included (mean
age: 83.9 years, 60.7% female). PlwD had a significantly higher in-hospital mortality rate (14.0% vs.
11.7%; OR 1.24, 95% CI: 1.16–1.32) than non-dementia controls. The highest excess mortality rate was
observed in the youngest age group (60–70 years: 10.9% vs. 5.7%; OR: 2.05, 95% CI: 1.30–3.24), decreased
with age, and became non-significant in the oldest age group (≥90 years: 16.2% vs. 17.3%;
OR: 0.93, 95% CI: 0.80–1.08). Significant differences were found for digestive system disorders (OR: 1.59;
95% CI: 1.15–1.89), cardiovascular and cerebrovascular disorders (OR: 1.51; 95% CI: 1.30–1.75), endocrine,
nutritional, and metabolic diseases (OR: 1.42; 95% CI: 1.06–1.90), and pneumonia (OR: 1.20;
95% CI: 1.04–1.37), as well as for all clinic departments except for geriatric departments. Conclusion: The
excess mortality rate was highest in younger age groups, where the general mortality and complication
rate is relatively low in the general population. Appropriate approaches are needed, especially in
non-geriatric wards. |
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| Descrizione del documento: | Gefördert durch den Open-Access-Publikationsfonds der UB Marburg. |
| Descrizione fisica: | 10 Seiten |
| DOI: | 10.3390/brainsci14050455 |