Passive Transfer of Animal-Derived Polyclonal Hyperimmune Antibodies Provides Protection of Mice from Lethal Lassa Virus Infection

Background: Lassa virus (LASV) can cause severe acute systemic infection in humans. No approved antiviral drugs or vaccines are currently available. Antibody-based therapeutics are considered a promising treatment strategy in the management of LASV disease. Methods: We used chimeric Ifnar?/? C57B...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Oestereich, Lisa, Müller-Kräuter, Helena, Pallasch, Elisa, Strecker, Thomas
Формат:	Өгүүллэг
Хэл сонгох:	англи
Хэвлэсэн:	Philipps-Universität Marburg 2023
Нөхцлүүд:	Medizin neutralizing antibodies; in vivo protection arenavirus Lassa mammarenavirus virus-like particle Lassa fever Medical sciences Medicine
Онлайн хандалт:	PDF-н бүрэн текст
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!