Sharing the wealth: The versatility of proteins targeted to peroxisomes and other organelles

Peroxisomes are eukaryotic organelles with critical functions in cellular energy and lipid metabolism. Depending on the organism, cell type, and developmental stage, they are involved in numerous other metabolic and regulatory pathways. Many peroxisomal functions require factors also relevant to oth...

Descrición completa

Gardado en:
Detalles Bibliográficos
Autoren: Bittner, Elena, Stehlik, Thorsten, Freitag, Johannes
Formato: Artigo
Idioma:inglés
Publicado: Philipps-Universität Marburg 2023
Schlagworte:
Acceso en liña:Texto completo PDF
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
Descripción
Zusammenfassung:Peroxisomes are eukaryotic organelles with critical functions in cellular energy and lipid metabolism. Depending on the organism, cell type, and developmental stage, they are involved in numerous other metabolic and regulatory pathways. Many peroxisomal functions require factors also relevant to other cellular compartments. Here, we review proteins shared by peroxisomes and at least one different site within the cell. We discuss the mechanisms to achieve dual targeting, their regulation, and functional consequences. Characterization of dual targeting is fundamental to understand how peroxisomes are integrated into the metabolic and regulatory circuits of eukaryotic cells.
descrición da copia:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
Descrición Física:17 Seiten
DOI:10.3389/fcell.2022.934331