Sharing the wealth: The versatility of proteins targeted to peroxisomes and other organelles

Peroxisomes are eukaryotic organelles with critical functions in cellular energy and lipid metabolism. Depending on the organism, cell type, and developmental stage, they are involved in numerous other metabolic and regulatory pathways. Many peroxisomal functions require factors also relevant to oth...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bittner, Elena, Stehlik, Thorsten, Freitag, Johannes
स्वरूप: लेख
भाषा:अंग्रेज़ी
प्रकाशित: Philipps-Universität Marburg 2023
विषय:
ऑनलाइन पहुंच:पीडीएफ पूर्ण पाठ
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विवरण
सारांश:Peroxisomes are eukaryotic organelles with critical functions in cellular energy and lipid metabolism. Depending on the organism, cell type, and developmental stage, they are involved in numerous other metabolic and regulatory pathways. Many peroxisomal functions require factors also relevant to other cellular compartments. Here, we review proteins shared by peroxisomes and at least one different site within the cell. We discuss the mechanisms to achieve dual targeting, their regulation, and functional consequences. Characterization of dual targeting is fundamental to understand how peroxisomes are integrated into the metabolic and regulatory circuits of eukaryotic cells.
वस्तु वर्णन:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
भौतिक वर्णन:17 Seiten
डिजिटल ऑब्जेक्ट पहचानकर्ता:10.3389/fcell.2022.934331