Investigation of the catalytic mechanism of RNase P: the role of divalent metal ions and functional groups important for catalysis
The ribonucleoprotein enzyme ribonuclease (RNase) P is an endonuclease that generates the mature 5' -ends of tRNA. Bacterial RNase P is composed of a large RNA subunit (P RNA) and a small protein (P protein). Studies with P RNA from E. coli and B. subtilis have implied a specific role for two o...
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格式: | Dissertation |
语言: | 英语 |
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Philipps-Universität Marburg
2006
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