TRAIL-dependent apoptosis of human peritoneal mesothelial cells by activated NK cells promotes ovarian cancer cell invasion in vitro

TRAIL-dependent apoptosis of human peritoneal mesothelial cells by activated NK cells promotes ovarian cancer cell invasion in vitro

Transcoelomic dissemination of tumor cells via the malignant peritoneal fluid (ascites) occurs at an early stage of high-grade serous ovarian carcinoma, enabling extensive tumor spreading within the peritoneum. A high quantity of malignant ascites arises during ovarian cancer progression, which is a...

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Bibliographic Details
Main Author: Steitz, Anna Mary
Contributors: Reinartz, Silke (Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
Invasion
T cells
T-Zellen
NK cells
NK-Zellen
Mesothelzellen
Medizin
Ovarialkarzinom
Ovarian cancer
Apoptose
Human peritoneal mesothelial cells
Apoptosis
Medical sciences Medicine
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