Characterization of histone acetyltransferase KAT6A and transcriptional repressor SAMD1 – two proteins possessing a novel class of unmethylated DNA-binding winged helix domains

Characterization of histone acetyltransferase KAT6A and transcriptional repressor SAMD1 – two proteins possessing a novel class of unmethylated DNA-binding winged helix domains

This thesis addresses the functions of two transcriptional regulators; histone acetyltransferase and transcriptional activator KAT6A (MOZ), and transcriptional repressor SAMD1 (Atherin), in their respective molecular and cell type-specific roles. Firstly, we identified a novel winged helix domain a...

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Bibliographische Detailangaben
1. Verfasser: Weber, Lisa Marie
Beteiligte: Liefke, Robert (PD Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
Epigenetik
Medizin
CpG-Inseln
DNS-Bindung
KAT6A
CpG islands
DNA-Methylierung
Histone
Acetylierung
DNA methylation
Medical sciences Medicine
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