Characterization of single point mutation in the gamma-carboxyglutamic acid domain of recombinant clotting Factor IX and its therapeutic potential
Hemophilia B (HB) is an inherited bleeding disorder caused by deficiency of FIX. The severity is classified based on the FIX activity level in the plasma. The trough levels of FIX activity in the circulation above 5% is considered the relevant parameter to maintain hemostasis. Even though rFIX produ...
Spremljeno u:
Glavni autor: | |
---|---|
Daljnji autori: | |
Format: | Dissertation |
Jezik: | engleski |
Izdano: |
Philipps-Universität Marburg
2023
|
Teme: | |
Online pristup: | PDF cijeli tekst |
Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
Internet
PDF cijeli tekstSignatura: |
urn:nbn:de:hebis:04-z2023-03593 |
---|---|
Datum izdanja: |
2023-12-21 |
Datum der Annahme: |
2023-04-27 |
Downloads: |
52 (2024), 1 (2023) |
Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
URL pristupa: |
https://archiv.ub.uni-marburg.de/diss/z2023/0359 https://doi.org/10.17192/z2023.0359 |