The intercellular signaling network in the tumor microenvironment of ovarian high-grade serous carcinoma

The intercellular signaling network in the tumor microenvironment of ovarian high-grade serous carcinoma

Ovarian high-gradeserous carcinoma (HGSC) is one of the most fatal malignancies in women. For this reason,it is of great importance to discover new potential targets for therapeutic intervention.Transcoelomic spread of tumor cells via malignant ascites,particularly to the omentum,is the major route...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Sommerfeld, Leah
Beteiligte: Müller, Rolf (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
Transkriptom
Tumormikroumgebung
tumor microenvironment
Metastasis
high-grade serous carcinoma
WNT4
mesothelial cell
Ovarialkarzinom
Metastase
Omentum
Makrophagen
Medizin
tumor-associated macrophages
Fibroblasten
cancer-associated fibroblast
Prostazyclin
Medical sciences Medicine
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