Elucidation of novel biosynthetic pathways for the discovery of cyclodipeptide derivatives from Streptomyces species

Harken, Lauritz Christian

Elucidation of novel biosynthetic pathways for the discovery of cyclodipeptide derivatives from Streptomyces species

Cyclodipeptides (CDPs) with a 2,5-diketopiperazine (DKP) as central core occur ubiquitously in living organisms, from simple bacteria and fungi to more complex ones like plants and animals. They display various biological and pharmacological effects, including antibiotic, antifungal, and antiprolife...

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Detalhes bibliográficos
Autor principal:	Harken, Lauritz Christian
Outros Autores:	Li, Shu-Ming (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Formato:	Dissertation
Idioma:	inglês
Publicado em:	Philipps-Universität Marburg 2022
Assuntos:	Biosynthese Cyclodipeptide Synthase Biosynthesis Cytochrome P450 Natural Products Fe(II)/2-Oxoglutarat abhängige Oxidase Cytochrom P-450 Cyclodipeptidoxidase Cyclodipeptide Oxidase Streptomyces Sekundärmetabolit Cyclodipeptidsynthase Pharmakologie, Therapeutik Fe(II)/2-Oxoglutarate dependent Oxidas Pr Pharmacology & therapeutics, prescription drugs
Acesso em linha:	Texto integral em PDF
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Elucidation of novel biosynthetic pathways for the discovery of cyclodipeptide derivatives from Streptomyces species

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