Dissecting the role of tyrosine phosphorylation of WAVE in macrophage migration

Dissecting the role of tyrosine phosphorylation of WAVE in macrophage migration

Cell migration is highly dependent on the precise orchestration of the assembly and disassembly of filamentous actin at their leading edge. Therefore, the temporal and spatial regulation of WAVE activity as the main regulator of Apr2/3 for branched actin polymerization is crucial for efficient lamel...

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Bibliographic Details
Main Author: Rüder, Marike
Contributors: Bogdan, Sven (Prof., Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2021
Subjects:
Migration
macrophages
Phosphorylierung
Drosophila
WAVE
Biowissenschaften, Biologie
Makrophagen
Aktin
Abelson
migration
phosphorylation
actin
Life sciences
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