Investigating the role of glial cells in neurodegenerative disorders by depleting astrocytes and oligodendrocytes in a model of amyloid-beta induced cytotoxicity in organotypic hippocampal slice cultures

The etiology of Alzheimer’s disease, the most common cause of dementia, is still under debate. On the molecular level, AD is characterized by the accumulation of the beta-Amyloid protein as well as neurofibrillary tangles. Additionally, evidence pinpoints to a crucial role of inflammatory processes...

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主要作者: Vidovic, Natascha
其他作者: Dodel, Richard (Prof. Dr. med.) (BetreuerIn (Doktorarbeit))
格式: Dissertation
語言:英语
出版: Philipps-Universität Marburg 2020
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