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Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design
The first topic of this thesis (Chapter 2) presents a mutational study performed on 17β-hydroxysteroid dehydrogenase type 14 (17β-HSD14) S205 variant. Five different mutations were done with respect to five amino acids which are believed to have an essential role in the enzyme activity and assembly....
保存先:
| 第一著者: | |
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| その他の著者: | |
| フォーマット: | Dissertation |
| 言語: | 英語 |
| 出版事項: |
Philipps-Universität Marburg
2021
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| 主題: | |
| オンライン･アクセス: | PDFフルテキスト |
| タグ: |
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PDFフルテキスト| 請求記号: |
urn:nbn:de:hebis:04-z2021-00954 |
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| 出版日付: |
2021-12-02 |
| Datum der Annahme: |
2020-11-06 |
| Downloads: |
34 (2024), 129 (2023), 119 (2022), 12 (2021) |
| Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
| アクセスURL: |
https://archiv.ub.uni-marburg.de/diss/z2021/0095 https://doi.org/10.17192/z2021.0095 |