Investigations toward the rational modulation of G protein-coupled receptor signalling pathways using in silico methods

Scharf, Magdalena Martina

Investigations toward the rational modulation of G protein-coupled receptor signalling pathways using in silico methods

G protein-coupled receptors (GPCRs) are one of the most important protein families and function as signal transducers located in the cell membrane. Currently, about one third of the marketed drugs target a GPCR, reflecting its importance in therapy and disease. Thus, it is not surprising that GPCRs...

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Bibliographische Detailangaben
1. Verfasser:	Scharf, Magdalena Martina
Beteiligte:	Kolb, Peter (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format:	Dissertation
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2021
Schlagworte:	Cannabinoid receptor 2 Adrenerger Rezeptor GPCR Molekulares Docking in silico Methoden in silico methods Molecular Docking Regulator of G protein Signalling Computational chemistry G-Protein gekoppelter Rezeptor MD Simulationen Pharmakologie beta-2 adrenergic receptor Docking <Chemie> Chemie MD Simulations beta-2-adrenerger Rezeptor, Cannabinoid Rezeptor 2 Chemistry & allied sciences
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Investigations toward the rational modulation of G protein-coupled receptor signalling pathways using in silico methods

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