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Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II
The data presented here show that different geometries of para-alkyl substituents of a benzenesulfonamide scaffold can have a significant influence on the thermodynamic and kinetic binding parameters and suggest, that the fine-tuning of the ligand geometry to match the geometry of the active site le...
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| Formato: | Dissertation |
| Lenguaje: | inglés |
| Publicado: |
Philipps-Universität Marburg
2020
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| Materias: | |
| Acceso en línea: | Texto Completo PDF |
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