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Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II
The data presented here show that different geometries of para-alkyl substituents of a benzenesulfonamide scaffold can have a significant influence on the thermodynamic and kinetic binding parameters and suggest, that the fine-tuning of the ligand geometry to match the geometry of the active site le...
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| 格式: | Dissertation |
| 语言: | 英语 |
| 出版: |
Philipps-Universität Marburg
2020
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| 主题: | |
| 在线阅读: | PDF-Volltext |
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PDF-Volltext| 索引号: |
urn:nbn:de:hebis:04-z2020-01231 |
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| Publikationsdatum: |
2020-12-22 |
| Datum der Annahme: |
2020-02-14 |
| Downloads: |
98 (2024), 159 (2023), 91 (2022), 55 (2021), 9 (2020) |
| Lizenz: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 访问URL: |
https://archiv.ub.uni-marburg.de/diss/z2020/0123 https://doi.org/10.17192/z2020.0123 |