Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

The data presented here show that different geometries of para-alkyl substituents of a benzenesulfonamide scaffold can have a significant influence on the thermodynamic and kinetic binding parameters and suggest, that the fine-tuning of the ligand geometry to match the geometry of the active site le...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yazar: Glöckner, Steffen
Diğer Yazarlar: Klebe, Gerhard Prof. Dr. (Tez danışmanı)
Materyal Türü: Dissertation
Dil:İngilizce
Baskı/Yayın Bilgisi: Philipps-Universität Marburg 2020
Konular:
Kinetik
Isotherme Titrationskalorimetrie
Protein-ligand interactions
Proteine
Ligand
Wirkstoffdesign
Protein-Ligand-Wechselwirkungen
Proteinkristallographie
Thermodynamics
Wirkstoff
Chemie
Wechselwirkung
Kinetics
Molekulardesign
Isothermalk titration calorimetry
Kristallographie
Drug design
Mikrokalorimetrie
Protein crystallography
Thermodynamik
Chemistry & allied sciences
Online Erişim:PDF Tam Metin
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Internet

PDF Tam Metin

Detaylı Erişim Bilgileri
Yer Numarası: urn:nbn:de:hebis:04-z2020-01231
Yayın Tarihi: 2020-12-22
Datum der Annahme: 2020-02-14
Downloads: 98 (2024), 159 (2023), 91 (2022), 55 (2021), 9 (2020)
Lizenz: https://creativecommons.org/licenses/by-nc-nd/4.0/
Erişim Adresi URL: https://archiv.ub.uni-marburg.de/diss/z2020/0123
https://doi.org/10.17192/z2020.0123

Benzer Materyaller