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Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II
The data presented here show that different geometries of para-alkyl substituents of a benzenesulfonamide scaffold can have a significant influence on the thermodynamic and kinetic binding parameters and suggest, that the fine-tuning of the ligand geometry to match the geometry of the active site le...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2020
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| 在线阅读: | PDF-Volltext |
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