Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

Trypanosoma brucei (T. brucei) is the causative agent of the Human African Trypanosomiasis (HAT), which is a neglected disease with an endemic occurrence in 36 sub-Saharan African countries. The current standard of care suffers from low efficacy and severe side effects. Therefore, new drugs with bet...

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Bibliographic Details
Main Author: Münzker Lena
Contributors: Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2019
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Call Number: urn:nbn:de:hebis:04-z2019-05006
Publication Date: 2020-05-25
Date of Acceptance: 2019-09-12
Downloads: 34 (2024), 176 (2023), 189 (2022), 239 (2021), 55 (2020)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2019/0500
https://doi.org/10.17192/z2019.0500