Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

Trypanosoma brucei (T. brucei) is the causative agent of the Human African Trypanosomiasis (HAT), which is a neglected disease with an endemic occurrence in 36 sub-Saharan African countries. The current standard of care suffers from low efficacy and severe side effects. Therefore, new drugs with bet...

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Bibliographic Details
Main Author: Münzker Lena
Contributors: Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:English
Published: Philipps-Universität Marburg 2019
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Call Number: urn:nbn:de:hebis:04-z2019-05006
Downloads: 231 (2021), 55 (2020)
Publication Date: 2020-05-25
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2019/0500
https://doi.org/10.17192/z2019.0500