Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

Hassaan, Engi

Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

There are several biophysical methods developed to rapidly identify weakly binding fragments to a target protein. X-ray crystallography provides structural information that is crucial for fragment optimization, however there are several criteria that must be met for a successful fragment screening...

ver descrição completa

Na minha lista:

Detalhes bibliográficos
Autor principal:	Hassaan, Engi
Outros Autores:	Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Formato:	Dissertation
Idioma:	inglês
Publicado em:	Philipps-Universität Marburg 2019
Assuntos:	drug discovery peroxin 14 NMR x-ray crystallography comparative analysis fragment screening SPR endothiapepsin tRNA guanine transglycosylase Pharmakologie, Therapeutik Pharmacology & therapeutics, prescription drugs
Acesso em linha:	Texto integral em PDF
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!

Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

Registos relacionados