Directed Evolution of an Fe(II)-Dependent Halogenase for Asymmetric C(sp3)-H Chlorination

Within this thesis, the chlorinase Wi-WelO15 from Westiella intricata UH strain HT-29-1 was explored for its evolvability towards non-natural substrates and its biocatalytic applicability. Organohalogens play an important role as pharmaceuticals and agricultural chemicals or synthetic intermediat...

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Bibliographic Details
Main Author: Düwel, Sabine
Contributors: Höbenreich, Sabrina (Dr. rer. nat.) (Thesis advisor)
Format: Dissertation
Language:English
Published: Philipps-Universität Marburg 2018
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Call Number: urn:nbn:de:hebis:04-z2018-05190
Downloads: 231 (2021), 100 (2020), 1 (2019)
Publication Date: 2019-12-05
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2018/0519
https://doi.org/10.17192/z2018.0519