RNA species in the host-pathogen dynamics during Legionella infection of human macrophages

RNA species in the host-pathogen dynamics during Legionella infection of human macrophages

Legionella pneumophila (L.p.) is a gram-negative, intracellular pathogen and a common cause of severe community-acquired pneumonia. In humans, L.p. replicates primarily within alveolar macrophages. It manipulates vital host cell functions such as vesicle trafficking and gene expression by the sec...

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Bibliographic Details
Main Author: Herkt, Christina Elena
Contributors: Schmeck, Bernd Thomas (Prof.Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2018
Subjects:
Legionella
pneumonia
Infektion
Medizin
infection
microRNAs
Pneumonie
dual RNA-sequencing
Makrophagen
host-pathogen interaction
Wirts-Pathogen-Interaktion
macrophages
Legionellen
Duale RNA-Sequenzierung
Medical sciences Medicine
Online Access:PDF Full Text
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