Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation
Dimethyl fumarate (DMF) is approved for treatment of relapsing remitting multiple sclerosis (RRMS), a chronic inflammatory disease of the central nervous system (CNS) that is caused by autoreactive T cells. The effect mechanism of DMF is not fully elucidated so far; however, a preferential impact on...
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Formato: | Dissertation |
Idioma: | inglês |
Publicado em: |
Philipps-Universität Marburg
2018
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Assuntos: | |
Acesso em linha: | Texto integral em PDF |
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Texto integral em PDFÁrea/Cota: |
urn:nbn:de:hebis:04-z2018-03301 |
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Publikationsdatum: |
2019-02-28 |
Datum der Annahme: |
2018-08-15 |
Downloads: |
45 (2024), 86 (2023), 69 (2022), 72 (2021), 76 (2020), 69 (2019) |
Lizenz: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2018/0330 https://doi.org/10.17192/z2018.0330 |