Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation

Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation

Dimethyl fumarate (DMF) is approved for treatment of relapsing remitting multiple sclerosis (RRMS), a chronic inflammatory disease of the central nervous system (CNS) that is caused by autoreactive T cells. The effect mechanism of DMF is not fully elucidated so far; however, a preferential impact on...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Lückel, Christina
Awduron Eraill: Huber, Magdalena (Prof. Dr.) (Cynghorydd traethodau ymchwil)
Fformat: Dissertation
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2018
Pynciau:
multiple sclerosis
IL-17
Multiple Sklerose
ROS
Tc17 cells
Dimethyl fumarate
Tc17 Zellen
Dimethylfumarat
Medizin
Medical sciences Medicine
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Manylion daliadau o
Rhif Galw: urn:nbn:de:hebis:04-z2018-03301
Dyddiad Cyhoeddi: 2019-02-28
Datum der Annahme: 2018-08-15
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Lizenz: https://creativecommons.org/licenses/by-nc-sa/4.0
URL mynediad: https://archiv.ub.uni-marburg.de/diss/z2018/0330
https://doi.org/10.17192/z2018.0330

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