Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation

Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation

Dimethyl fumarate (DMF) is approved for treatment of relapsing remitting multiple sclerosis (RRMS), a chronic inflammatory disease of the central nervous system (CNS) that is caused by autoreactive T cells. The effect mechanism of DMF is not fully elucidated so far; however, a preferential impact on...

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Autor principal: Lückel, Christina
Altres autors: Huber, Magdalena (Prof. Dr.) (Assessor de tesis)
Format: Dissertation
Idioma:anglès
Publicat: Philipps-Universität Marburg 2018
Matèries:
multiple sclerosis
IL-17
Multiple Sklerose
ROS
Tc17 cells
Dimethyl fumarate
Tc17 Zellen
Dimethylfumarat
Medizin
Medical sciences Medicine
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Signatura: urn:nbn:de:hebis:04-z2018-03301
Data de publicació: 2019-02-28
Datum der Annahme: 2018-08-15
Downloads: 58 (2024), 86 (2023), 69 (2022), 72 (2021), 76 (2020), 69 (2019)
Lizenz: https://creativecommons.org/licenses/by-nc-sa/4.0
URL d'accés: https://archiv.ub.uni-marburg.de/diss/z2018/0330
https://doi.org/10.17192/z2018.0330

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