Dimethyl fumarate suppresses Tc17 cell fate in autoimmunity via ROS accumulation
Dimethyl fumarate (DMF) is approved for treatment of relapsing remitting multiple sclerosis (RRMS), a chronic inflammatory disease of the central nervous system (CNS) that is caused by autoreactive T cells. The effect mechanism of DMF is not fully elucidated so far; however, a preferential impact on...
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Format: | Dissertation |
Jezik: | angleščina |
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Philipps-Universität Marburg
2018
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