Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway
Hedgehog signaling plays a vital role in regulating varied fundamental processes including embryonic development, proliferation, and differentiation. Aberrant hedgehog signaling has been one of the reason for cancers such as Basal cell carcinoma (BCC), rhabdomyosarcoma (RMS) and medulloblastoma (MB)...
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格式: | Dissertation |
语言: | 英语 |
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Philipps-Universität Marburg
2017
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