Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Hedgehog signaling plays a vital role in regulating varied fundamental processes including embryonic development, proliferation, and differentiation. Aberrant hedgehog signaling has been one of the reason for cancers such as Basal cell carcinoma (BCC), rhabdomyosarcoma (RMS) and medulloblastoma (MB)...

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Autor principal: Dhanyamraju, Pavan Kumar
Outros Autores: Lauth, Matthias (PD Dr,) (Orientador)
Formato: Dissertation
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2017
Assuntos:
HDAC6
Medizin
Embryonic development
Embryogenese
Hedgehog signaling
Hedgehog Signalweg
Medical sciences Medicine
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