Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Hedgehog signaling plays a vital role in regulating varied fundamental processes including embryonic development, proliferation, and differentiation. Aberrant hedgehog signaling has been one of the reason for cancers such as Basal cell carcinoma (BCC), rhabdomyosarcoma (RMS) and medulloblastoma (MB)...

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Bibliografski detalji
Glavni autor: Dhanyamraju, Pavan Kumar
Daljnji autori: Lauth, Matthias (PD Dr,) (Savjetnik disertacije)
Format: Dissertation
Jezik:engleski
Izdano: Philipps-Universität Marburg 2017
Teme:
HDAC6
Medizin
Embryonic development
Embryogenese
Hedgehog signaling
Hedgehog Signalweg
Medical sciences Medicine
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