Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Hedgehog signaling plays a vital role in regulating varied fundamental processes including embryonic development, proliferation, and differentiation. Aberrant hedgehog signaling has been one of the reason for cancers such as Basal cell carcinoma (BCC), rhabdomyosarcoma (RMS) and medulloblastoma (MB)...

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Bibliographic Details
Main Author: Dhanyamraju, Pavan Kumar
Contributors: Lauth, Matthias (PD Dr,) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2017
Subjects:
HDAC6
Medizin
Embryonic development
Embryogenese
Hedgehog signaling
Hedgehog Signalweg
Medical sciences Medicine
Online Access:PDF Full Text
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