Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway

Hedgehog signaling plays a vital role in regulating varied fundamental processes including embryonic development, proliferation, and differentiation. Aberrant hedgehog signaling has been one of the reason for cancers such as Basal cell carcinoma (BCC), rhabdomyosarcoma (RMS) and medulloblastoma (MB)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Dhanyamraju, Pavan Kumar
Awduron Eraill: Lauth, Matthias (PD Dr,) (Cynghorydd traethodau ymchwil)
Fformat: Dissertation
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2017
Pynciau:
HDAC6
Medizin
Embryonic development
Embryogenese
Hedgehog signaling
Hedgehog Signalweg
Medical sciences Medicine
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