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Beyond Affinity: Drug-Kinase Interaction Put under the Microscope
Over the last 20 years, the consideration of biophysical parameters such as kinetics and thermodynamics has been used to guide modern drug design. In contrast to the classical approach that mainly relies on affinity optimization, biophysical parameters allow a further discrimination of potential dru...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2017
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| 在线阅读: | PDF-Volltext |
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