Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin
In the pre-clinical development stages of most drug design campaigns, the equilibrium binding affinity of a prospective lead candidate, in the form of an IC50, Kd or ΔG° value, is the most commonly employed benchmark parameter for its effectiveness as a putative drug. Hydrogen bonding, van der Waals...
Na minha lista:
Autor principal: | |
---|---|
Outros Autores: | |
Formato: | Dissertation |
Idioma: | inglês |
Publicado em: |
Philipps-Universität Marburg
2017
|
Assuntos: | |
Acesso em linha: | Texto Completo em Formato PDF |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|