Establishment and characterization of preclinical mouse models for evaluation of oncogenic and tumor-suppressive properties of p53 family members

Establishment and characterization of preclinical mouse models for evaluation of oncogenic and tumor-suppressive properties of p53 family members

Cancer development is a multistep process which leads to tumors composed of diverse cell populations originating from one cell which underwent differential genetic changes over time. Within one tumor, such heterogeneity provides distinct subpopulations with selection advantages promoting metastasis...

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Autore principale: Fuchs, Jeannette
Altri autori: Stiewe, Thorsten (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2016
Soggetti:
Biowissenschaften, Biologie
p53 p73 tumor biology
p53 p73 Tumorbiologie
Life sciences
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Collocazione: urn:nbn:de:hebis:04-z2017-02859
Data di pubblicazione: 2017-04-27
Datum der Annahme: 2017-03-22
Downloads: 28 (2024), 89 (2023), 68 (2022), 60 (2021), 70 (2020), 67 (2019), 7 (2018)
Lizenz: https://creativecommons.org/licenses/by-nc-sa/4.0
URL di accesso: https://archiv.ub.uni-marburg.de/diss/z2017/0285
https://doi.org/10.17192/z2017.0285

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